Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tbr1  T-box brain transcription factor 1   (Synonyms: T-box brain gene 1)
Results	Reference
1	J:194545 Alsio JM, Tarchini B, Cayouette M, Livesey FJ, Ikaros promotes early-born neuronal fates in the cerebral cortex. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E716-25
1	J:182157 Baranek C, Dittrich M, Parthasarathy S, Bonnon CG, Britanova O, Lanshakov D, Boukhtouche F, Sommer JE, Colmenares C, Tarabykin V, Atanasoski S, Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3546-51
1	J:282886 Blackwood CA, Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone. Neuroscience. 2019 Aug 10;413:230-238
1	J:244667 Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, Yoshida Y, Simons M, Chauvet S, Mann F, Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nat Commun. 2017 Feb 22;8:14508
1	J:225805 Chen C, Lee GA, Pourmorady A, Sock E, Donoghue MJ, Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes. J Neurosci. 2015 Jul 22;35(29):10629-42
1	J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712
1	J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401
1	J:157097 Cocas LA, Miyoshi G, Carney RS, Sousa VH, Hirata T, Jones KR, Fishell G, Huntsman MM, Corbin JG, Emx1-lineage progenitors differentially contribute to neural diversity in the striatum and amygdala. J Neurosci. 2009 Dec 16;29(50):15933-46
1	J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93
1*	J:208031 Croquelois A, Giuliani F, Savary C, Kielar M, Amiot C, Schenk F, Welker E, Characterization of the HeCo mutant mouse: a new model of subcortical band heterotopia associated with seizures and behavioral deficits. Cereb Cortex. 2009 Mar;19(3):563-75
1	J:228347 Daviaud N, Chen K, Huang Y, Friedel RH, Zou H, Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant. Dev Neurobiol. 2016 Aug;76(8):882-99
1	J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84
1	J:241499 Del Toro D, Ruff T, Cederfjall E, Villalba A, Seyit-Bremer G, Borrell V, Klein R, Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules. Cell. 2017 May 04;169(4):621-635.e16
1	J:244825 Dennis DJ, Wilkinson G, Li S, Dixit R, Adnani L, Balakrishnan A, Han S, Kovach C, Gruenig N, Kurrasch DM, Dyck RH, Schuurmans C, Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4934-E4943
1	J:236353 Dudok JJ, Murtaza M, Henrique Alves C, Rashbass P, Wijnholds J, Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon. Neurosci Res. 2016 Jul;108:12-23
1	J:226378 Falk S, Joosten E, Kaartinen V, Sommer L, Smad4 and Trim33/Tif1gamma redundantly regulate neural stem cells in the developing cortex. Cereb Cortex. 2014 Nov;24(11):2951-63
1	J:106708 Fink AJ, Englund C, Daza RA, Pham D, Lau C, Nivison M, Kowalczyk T, Hevner RF, Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J Neurosci. 2006 Mar 15;26(11):3066-76
1	J:333383 Funk OH, Qalieh Y, Doyle DZ, Lam MM, Kwan KY, Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2116956119
1	J:266542 Hasenpusch-Theil K, West S, Kelman A, Kozic Z, Horrocks S, McMahon AP, Price DJ, Mason JO, Theil T, Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression. Development. 2018 Aug 20;145(17):dev163147
1	J:173598 Jacquet BV, Muthusamy N, Sommerville LJ, Xiao G, Liang H, Zhang Y, Holtzman MJ, Ghashghaei HT, Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb. J Neurosci. 2011 Jun 22;31(25):9368-82
1	J:178681 Lakoma J, Garcia-Alonso L, Luque JM, Reelin sets the pace of neocortical neurogenesis. Development. 2011 Dec;138(23):5223-34
1	J:343553 Larrigan S, Joshi SV, Mattar P, Divergent phenotypes in constitutive versus conditional mutant mouse models of Sifrim-Hitz-Weiss syndrome. Hum Mol Genet. 2023 Dec 1;32(24):3361-3373
1	J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49
1	J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93
1	J:231963 Matsumoto S, Banine F, Feistel K, Foster S, Xing R, Struve J, Sherman LS, Brg1 directly regulates Olig2 transcription and is required for oligodendrocyte progenitor cell specification. Dev Biol. 2016 May 15;413(2):173-87
1	J:177127 McCarthy DM, Zhang X, Darnell SB, Sangrey GR, Yanagawa Y, Sadri-Vakili G, Bhide PG, Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain. J Neurosci. 2011 Sep 21;31(38):13400-11
1	J:304361 Mitsogiannis MD, Pancho A, Aerts T, Sachse SM, Vanlaer R, Noterdaeme L, Schmucker D, Seuntjens E, Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. 2020;8:624181
1	J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9
1*	J:117267 Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii M, Flavell RA, Rakic P, MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801
1	J:199787 Saurat N, Andersson T, Vasistha NA, Molnar Z, Livesey FJ, Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Neural Dev. 2013;8:14
1	J:195360 Seibt J, Armant O, Le Digarcher A, Castro D, Ramesh V, Journot L, Guillemot F, Vanderhaeghen P, Bouschet T, Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon. PLoS One. 2012;7(11):e48675
1	J:154601 Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V, Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci. 2009 Nov;12(11):1373-80
1	J:304006 Shi X, Lim Y, Myers AK, Stallings BL, Mccoy A, Zeiger J, Scheck J, Cho G, Marsh ED, Mirzaa GM, Tao T, Golden JA, PIK3R2/Pik3r2 Activating Mutations Result in Brain Overgrowth and EEG Changes. Ann Neurol. 2020 Dec;88(6):1077-1094
1	J:285212 Shohayeb B, Ho U, Yeap YY, Parton RG, Millard SS, Xu Z, Piper M, Ng DCH, The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. Hum Mol Genet. 2020 Jan 15;29(2):248-263
1	J:308820 Shohayeb B, Ho UY, Hassan H, Piper M, Ng DCH, The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus. Front Cell Dev Biol. 2020;8:549353
1	J:137035 Solberg N, Machon O, Krauss S, Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool. Dev Dyn. 2008 Jul;237(7):1799-811
1	J:298594 Stepien BK, Naumann R, Holtz A, Helppi J, Huttner WB, Vaid S, Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion. Curr Biol. 2020 Nov 2;30(21):4227-4237.e5
1	J:203999 Svoboda DS, Paquin A, Park DS, Slack RS, Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis. Dev Biol. 2013 Dec 1;384(1):101-13
1*	J:248338 Teoh JJ, Iwano T, Kunii M, Atik N, Avriyanti E, Yoshimura SI, Moriwaki K, Harada A, BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain. PLoS One. 2017;12(4):e0175888
1	J:197141 Tuoc TC, Boretius S, Sansom SN, Pitulescu ME, Frahm J, Livesey FJ, Stoykova A, Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness. Dev Cell. 2013 May 13;25(3):256-69
1	J:170348 Westerlund N, Zdrojewska J, Padzik A, Komulainen E, Bjorkblom B, Rannikko E, Tararuk T, Garcia-Frigola C, Sandholm J, Nguyen L, Kallunki T, Courtney MJ, Coffey ET, Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate. Nat Neurosci. 2011 Mar;14(3):305-13
1	J:292913 Will L, Portegies S, van Schelt J, van Luyk M, Jaarsma D, Hoogenraad CC, Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo. Acta Neuropathol Commun. 2019 Oct 26;7(1):162
1	J:293436 Wilson SL, Kalinovsky A, Orvis GD, Joyner AL, Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types. Cerebellum. 2011 Sep;10(3):356-72
1*	J:124867 Wrobel CN, Mutch CA, Swaminathan S, Taketo MM, Chenn A, Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. Dev Biol. 2007 Sep 15;309(2):285-97
1	J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272
1	J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674
1	J:261356 Zhou ZW, Tapias A, Bruhn C, Gruber R, Sukchev M, Wang ZQ, DNA damage response in microcephaly development of MCPH1 mouse model. DNA Repair (Amst). 2013 Aug;12(8):645-55